long-chain PFAS

Chemical manufacturers are planning to gradually ramp down sales of certain short-chain per- and polyfluoroalkyl substances (PFAS) used as grease-proofing agents on fast food wrappers, take-out containers, and other paper-based food packaging, the US Food and Drug Administration announced July 31.

AGC Chemicals Americas, Archroma Management, and Daikin America will phase out sales of substances that contain 6:2 fluorotelomer alcohol (6:2 FTOH) for use in paper and cardboard food packaging beginning in January 2021. The process is expected to take 3 years, with up to an additional 18 months to use up existing stocks. A fourth company, Chemours, told the FDA last year that it has already stopped selling the substances in the US market.

PFAS that contain 6:2 FTOH replaced long-chain PFAS in food packaging nearly a decade ago because of concerns about the safety of long-chain PFAS, which are linked to cancer and immune disorders. FDA scientists, however, are now questioning the safety of those replacements. Data from rodent studies suggest that 6:2 FTOH accumulates in the body, the FDA reported in January (Toxicol. Appl. Pharmacol. 2020, DOI: 10.1016/j.taap.2020.114878).

“The data suggest the potential of 6:2 FTOH to also persist in humans from chronic dietary exposure,” the FDA says in a statement. “Further scientific studies are needed to better understand the potential human health risks from dietary exposure to food-contact substances that contain 6:2 FTOH.”

Rather than conduct those tests, the three manufacturers of the substances in question agreed to phase out sales in the US. – read the full story and report at C&EN.